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超滤技术在生物酶分离中的研究进展
引用本文:张剑,王境. 超滤技术在生物酶分离中的研究进展[J]. 精细化工, 2019, 36(5): 786-795
作者姓名:张剑  王境
作者单位:山西大学化学化工学院,山西太原,030006;山西大学化学化工学院,山西太原,030006
基金项目:2016年度山西省重点研发计划国际合作资助项目(20163D421029)
摘    要:该文综述了超滤技术的原理、分离过程、发酵液的性质以及超滤膜和超滤条件对生物酶超滤性能的影响。并从发酵液的处理、超滤膜和超滤过程的优化三方面出发,对近期提高超滤性能取得的成果进行了总结和讨论。最后指出生物酶超滤技术的未来发展方向有以下几点:超滤数学模型的开发;提高酶的稳定性;超滤膜的改进和开发;超滤工艺的改进。

关 键 词:  超滤    纯化  优化
收稿时间:2018-08-28
修稿时间:2018-12-17

Research progress of ultrafiltration in the separation of biological enzymes
ZHANG Jian and Wang Jing. Research progress of ultrafiltration in the separation of biological enzymes[J]. Fine Chemicals, 2019, 36(5): 786-795
Authors:ZHANG Jian and Wang Jing
Affiliation:College of Chemistry and Chemical Engineering, Shanxi University
Abstract:In this paper, the ultrafiltration in separation of biological enzymes was reviewed, including the principle of ultrafiltration technology, separation process as well as the effects of fermentation broth properties, ultrafiltration membranes and ultrafiltration conditions on the ultrafiltration performance of biological enzymes. Meanwhile, the recent achievements in improving the ultrafiltration performance were summarized and discussed in three aspects of fermentation liquid treatment, ultrafiltration membranes and ultrafiltration process optimization. Finally, it is considered that the future development directions of biological enzymes ultrafiltration technology are as follows: the development of ultrafiltration mathematical models; the improvement of enzyme stability; the improvement and development of ultrafiltration membranes; the improvement of ultrafiltration technology.
Keywords:enzyme   ultrafiltration   membrane   purification   optimization
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