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Strength retention of self-reinforced poly-L-lactide screws and plates: anin vivo andin vitro study
Authors:R. Suuronen  T. Pohjonen  R. Taurio  P. Törmälä  L. Wessman  K. Rönkkö  S. Vainionpää
Affiliation:(1) Department of Oral and Maxillofacial Surgery, University of Helsinki, Mannerheimintie 172, 00300 Helsinki, Finland;(2) Biomaterials Laboratory, Institute of Plastics Technology, Tampere University of Technology, PO Box 527, 33101 Tampere, Finland;(3) Department of Surgery, College of Veterinary Medicine, Hämeentie 157, 00580 Helsinki, Finland;(4) Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, 00260 Helsinki, Finland
Abstract:Self-reinforced poly-L-lactide (SR-PLLA) screws and multilayer plates were studied for their initial mechanical shear and/or tensile strength and strength retentionin vivo andin vitro up to 48 weeks. The plates were studiedin vitro up to 68 weeks. The loss of strength was fasterin vivo thanin vitro. The screws retained more than half of their initial shear strength up to 12 weeksin vivo and over 24 weeksin vitro. By 48 weeks they had lost nearly all of their mechanical strength in both groups. The plates retained over 54% of their initial tensile and 71% of shear strength up to 24 weeksin vivo. The shear strength did not particularly diminish up to 52 weeks of follow-upin vitro whereas the tensile strength was slightly decreased after 36 weeks. After this follow-up time the loss of strength was more rapid and by 68 weeks the shear strength had decreased to 17% and the tensile strength to 0%.
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