Predictive model on micro droplet generation through mechanical cutting |
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Authors: | Woon Seob Lee Sachin Jambovane Duckjong Kim Jong Wook Hong |
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Affiliation: | (1) Materials Research and Education Center, Department of Mechanical Engineering, Auburn University, Auburn, AL 36849, USA |
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Abstract: | We describe the step-by-step formation process of picoliter to femtoliter volume of microdroplets by using a mechanical valve.
An experiment-based theoretical model has been proposed through a parametric study of droplet formation in a microchannel
with variations of the channel height, the working pressure to drive the liquids in the microchannels, and the viscosity of
the dispensed phase. Three steps in the process of droplet generation have been depicted. The present study provides a clear
understanding of the droplet generation process based on physical cutting method by using a mechanical valve and could be
applied to advanced design for highly flexible droplet-based microfluidic systems.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users.
W. S. Lee, S. Jambovane and D. Kim contributed equally to this work. |
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