A reliable integrative autocorrelator device for particle fluctuation rate monitoring |
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| Affiliation: | 1. State Key Lab of Electronic Thin Films & Integrated Devices, University of Electronic Science & Technology of China, Chengdu, China;2. Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, 300192 Tianjin, China;3. Design center, Avic Beijing Keeven Aviation Instrument CO., LTD, China Aviation Industry Corporation, Beijing, China;1. Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran;2. Delft University of Technology, EEMCS Faculty, Delft, The Netherlands;1. Department of Electrical Engineering, National Taiwan Normal University, Taiwan;2. Institute of Electronics, National Chiao Tung University, Taiwan;1. Department of Electrophysics, National Chiao Tung University, Hsinchu 300, Taiwan, ROC;2. Department of Mechanical Engineering, National Chiao Tung University, Hsinchu 300, Taiwan, ROC;3. Department of Mechanical Engineering, National Chung Cheng University, Chia-Yi 621, Taiwan, ROC;4. Research Group of Biomedical Image Processing, Shing-Tung Yau Center, National Chiao Tung University, Hsinchu 300, Taiwan, ROC;5. Department of Electronics Engineering, National Chiao Tung University, Hsinchu 300, Taiwan, ROC;6. Material and Design Engineering Division Engineering Center, Siliconware Precision Industries Co., Ltd., Taichung 400, Taiwan, ROC;7. Department of Mechatronic Engineering, National Taiwan Normal University, Taipei City 106, Taiwan, ROC;1. Department of Manufacturing and Materials Engineering, University of Campinas, UNICAMP, 13083-860 Campinas, SP, Brazil;2. Federal Institute of Education, Science and Technology of Pará, IFPA, 66093-020 Belém, PA, Brazil |
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| Abstract: | The monitoring of particle fluctuation rate is of great importance in the biomedical field, especially in applications concerning the near-infrared spectroscopy (NIRS) monitoring of blood flow. Blood flow is one of the most important indexes to estimate the body functional status, while the existing technologies for its measurements have some limitations. NIRS is non-invasive, continuous real-time, applicable to blood flow monitoring of a variety of vessel sizes and deeper depths. Autocorrelation module, which is capable of processing optical signals and getting blood flow data with the upper computer module, is an important part of near-infrared monitoring blood flow method. In this study, we integrated the upper computer module into the autocorrelator device, reduced man-made errors caused by multiple modules, and made the device more convenient and reliable. We also tested its performance and reliability. The result showed that the device has great potentiality in measuring the particle fluctuation rate conveniently, accurately and reliably. In future, the device will be tested in noninvasive clinic trials to verify its monitoring effects. |
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