| 应用MATLAB优化十五碳二元酸发酵培养基 |
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| 引用本文： | 王丽菊,余晓斌,胥九兵. 应用MATLAB优化十五碳二元酸发酵培养基[J]. 计算机与应用化学, 2009, 26(1) |
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| 作者姓名： | 王丽菊 余晓斌 胥九兵 |
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| 作者单位： | 江南大学生物工程学院,江苏,无锡,214122;江南大学工业生物技术教育部重点实验室,江苏,无锡,214122 |
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| 摘 要： | 为提高十五碳二元酸(DC15)产量,利用均匀设计法考察DC15发酵培养基组分尿素、乙酸钠、磷酸二氢钾对DC15发酵的影响,并利用MATLAB 7.1的逐步回归函数(stepwise)、多元线性回归函(regress)、二次规划优化函数(quadprog)等分析数据,得到最佳组合(W/V):尿素0.05%,乙酸钠0.37%,磷酸二氢钾0.91%.实验结果表明,采用优化后的培养基,DC15产量达到29.54 g/L,比初始培养基条件下22.04 g/.L提高了34%.
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| 关 键 词： | 逐步回归 二次规划优化函数 十五碳二元酸 MATLAB |
Medium optimization for pentadecane-dioic acid based on MATLAB |
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| Wang Liju,Yu Xiaobin,Xu Oiubing. Medium optimization for pentadecane-dioic acid based on MATLAB[J]. Computers and Applied Chemistry, 2009, 26(1) |
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| Authors: | Wang Liju Yu Xiaobin Xu Oiubing |
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| Affiliation: | 1.School of Biotechnology;Jiangnan University;Wuxi;214122;Jiangsu;China;2.The Key Laboratory of Industrial Biotechnology;Ministry of Education;China |
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| Abstract: | To improve the yield of pentadecane-dioic acid(DC_(15)),the uniform design and MATLAB 7.1 were employed to study the influences of urea,monobasic potassium phosphate and sodium acetate in the fermentation of DC_(15).Using applications of stepwise,re- gress and quadprog in analysis the data,obtained the optimum medium:urea 0.05%,monobasic potassium phosphate 0.91%,sodi- um acetate 0.37%.The yield of DC_(15)has improved 34% under the optimum medium. |
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| Keywords: | MATLAB |
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