In vitro remineralization of human dental enamel by bioactive glasses |
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Authors: | Zhihong?Dong Email author" target="_blank">Jiang?ChangEmail author Yue?Zhou Kaili?Lin |
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Affiliation: | (1) State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, The People’s Republic of China;(2) Med-X Research Institute of Shanghai Jiao Tong University, 1954 Hua Shan Road, Shanghai, 200030, The People’s Republic of China; |
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Abstract: | Different compositions of silicate-based bioactive glasses of the system SiO2–CaO–P2O5 (45S, 58S, and 77S) were evaluated for teeth remineralization effect on the etched human dental enamel in simulate human
oral environment. Enamel samples were subjected to demineralization in citric acid solution, then treated with different bioactive
glass pastes, and finally soaked in simulated oral fluid (SOF) for 7 days before evaluation. The results indicated that enamel
surface formed a homogenous and dense mineralized layer with the treatment of 45S and 58S samples. The average thickness was
4 and 2.5 μm, respectively. But 77S treatment showed a loose and uneven remineralized layer. Although the surface roughness
decreased with the increase of silicon content, mechanical strength of enamel samples became less gradually. Taken together,
45S paste had the best remineralization ability, best mechanical strength, and satisfactory surface roughness. These results
also indicated that the level of silicon content of bioactive glasses played a key role in dental enamel remineralization. |
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