| 辅酶Q10的合成与应用 |
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| 引用本文： | 毛进,沈秉石,金国荣. 辅酶Q10的合成与应用[J]. 精细与专用化学品, 2005, 13(10): 22-24 |
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| 作者姓名： | 毛进 沈秉石 金国荣 |
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| 作者单位： | 海门市通联化工有限公司,江苏,海门,226100 |
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| 摘 要： | 以茄尼醇、异戊二烯和辅酶Q0作为主要原料,通过溴化、加成和缩合3步反应合成了目标产物辅酶Q10.其中溴化和加成反应一次收率分别为95%和90%,缩合反应重复收率在70%左右.生产规模为5kg/次.并介绍了辅酶Q10的应用和市场需求.
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| 关 键 词： | 辅酶Q10 茄尼醇 异戊二烯 半合成法 |
| 修稿时间： | 2005-01-31 |
Synthesis and Application of Coenzyme Q10 |
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| Mao Jin,SHEN Bing-shi,JIN Guo-rong. Synthesis and Application of Coenzyme Q10[J]. Fine and Specialty Chemicals, 2005, 13(10): 22-24 |
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| Authors: | Mao Jin SHEN Bing-shi JIN Guo-rong |
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| Abstract: | Using solanesol, isoprene and coenzyme Q 0 as main raw materials, title compound coenzyme Q 10 was synthesized through reactions with three steps i.e. bromination, addition and condensation. The conversion yield per pass of bromination and addition reaction was 95% and 90% separately, and repetitive yield of condensation was about 70%. Meanwhile, the applications and market demand on coenzyme Q 10 were introduced. |
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| Keywords: | coenzyme Q_(10) solanesol isoprene semi-synthesis method |
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