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BMP-2 Long-Term Stimulation of Human Pre-Osteoblasts Induces Osteogenic Differentiation and Promotes Transdifferentiation and Bone Remodeling Processes
Authors:Lena-Christin Ingwersen  Marcus Frank  Hendrik Naujokat  Klaas Loger  Rainer Bader  Anika Jonitz-Heincke
Affiliation:1.Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, 18057 Rostock, Germany;2.Medical Biology and Electron Microscopic Center, Rostock University Medical Center, 18057 Rostock, Germany;3.Department of Life, Light and Matter, University of Rostock, 18059 Rostock, Germany;4.Department of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, 24105 Kiel, Germany; (H.N.); (K.L.)
Abstract:
Keywords:BMP-2   pre-osteoblasts   osteoblastogenesis   bone regeneration   bone homeostasis   intracellular vacuoles
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