交联三维网络结构PINPAm的制备及其性能研究

聚N-异丙基丙烯酰胺(PINPAm)水凝胶是一种亲水但不溶于水,具有交联三维网络结构的高分子聚合物,具有一定条件下的溶胀/退溶胀行为,同时具有输送和渗透性、能量转换、吸附分离、生物相容性等功能。本文研究了用不同量的引发剂过硫酸铵(APS)对水凝胶形成的影响;反应温度分别为低温(低于5℃、20℃、30℃、40℃对水凝胶形成的影响。所制备的PNIPAm水凝胶分别测定了相转变温度(LCST)和凝胶溶胀率(SR)。结果表明引发剂量用量增多时水凝胶形成反应时间变短;反应温度升高水凝胶外观出现由无色透明凝胶→乳白半透明凝胶→乳白色凝胶→乳白色且无固定形态凝胶的变化。低温生成的水凝胶相转变温度(LCST)在33~34℃之间,水凝胶体积发生不连续收缩现象;交联剂N,N-亚甲基双丙烯酞胺(BIS)使用量越多溶胀率越小。

Preparation and properties of crosslinked three dimensional network structure PNIPAm

Poly(N-isopropylacrylamide)(PNIPAm)hydrogel is a hydrophilic but water-soluble polymer with cross-linked three-dimensional network structure.It has swelling and deswelling behavior under certain conditions,and has the functions of transportation and permeability,energy conversion,adsorption and separation,biocompatibility and so on.The effect of ammonium persulfate(APS)initiator with different amount on the formation of hydrogel was studied.The reaction temperature was low temperature(below 5℃,20℃,30℃and 40℃).The phase transition temperature(LCST)and gel swelling ratio(SR)of the PNIPAm hydrogel were measured.The results showed that the reaction time of hydrogel was shorter when the dosage of initiator increased;The appearance of hydrogel changed from colorless transparent gel to opaque gel to milky white gel to milky white without fixed gel.The phase transition temperature(LCST)of the hydrogel generated at low temperature was between 33~34℃,The volume of hydrogel was discontinuous;The more N,N-methylenebispropenylphthaline(BIS)was used,the smaller the swelling rate was.