3H]LY341495, a highly potent, selective and novel radioligand for labeling Group II metabotropic glutamate receptors |
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| Authors: | PL Ornstein MB Arnold TJ Bleisch RA Wright WJ Wheeler DD Schoepp |
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| Affiliation: | Lilly Research Laboratories, Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285-0510, USA. |
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| Abstract: | We report herein the synthesis and pharmacological characterization of a tritiated version of the potent and selective cyclopropyl amino acid LY341495 as a radioligand to label group II metabotropic glutamate receptors in rat brain homogenates. |
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