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Solubilization of Single-walled Carbon Nanotubes with Single-stranded DNA Generated from Asymmetric PCR |
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| Authors: | Zhiqiang Liang Ruojun Lao Jing Wang Yongbiao Liu Lihua Wang Qing Huang Shiping Song Genxi Li Chunhai Fan |
| Affiliation: | 1.Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China; E-mail: (for Genxi Li);2.Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, P. R. China; E-mail: (for Shiping Song);3.The People’s Hospital of Jiangsu Province, Nanjing 210029, P. R. China |
| Abstract: | Carbon nanotubes (CNTs) can be effectively dispersed and functionalized by wrapping with long single-stranded DNA (ssDNA) synthesized by asymmetric PCR. The ssDNA-CNTs attached on surface of glass carbon electrode made it possible for electrochemical analysis and sensing, which was demonstrated by reduction of H2O2 on hemoglobin/ssDNA-CNTs modified electrodes. This research showed the potential application of DNA-functionalised CNTs in construction of future electrochemical biosensors. |
| Keywords: | Carbon nanotubes (CNTs) single-stranded DNA (ssDNA) asymmetric PCR electrochemical biosensor |