Molecular dynamics simulations of the unfolding of {beta}2-microglobulin and its variants |
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Authors: | Ma, Buyong Nussinov, Ruth |
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Affiliation: | 1Basic Research Program, SAICFrederick, Inc., Laboratory of Experimental and Computational Biology, NCI-FCRDC, Frederick, MD 21702, USA and 2Sackler Institute of Molecular Medicine, Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel |
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Abstract: | In this study, we examined the unfolding processes of nativeß2-microglobulin and two related variants, one withan N-terminal hexapeptide deletion |
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