In vitro bioactivity of chitosan/poly (d,l-lactide-co-glycolide) composites |
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Authors: | S.A. Martel-Estrada,C.A. Martí nez-Pé rezJ.G. Chacó n-Nava,P.E. Garcí a-CasillasI. Olivas-Armendá riz |
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Affiliation: | a Centro de Investigación en Materiales Avanzados, Departamento de Física de Materiales, Miguel de Cervantes 120, Complejo Industrial Chihuahua, C.P. 31109, Chihuahua, Mexicob Instituto de Ingeniería y Tecnología, Universidad Autónoma de Cd. Juárez, Av. Del Charro 450 Norte, Col. Partido Romero, C.P. 32310, Cd. Juárez, Chihuahua, Mexico |
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Abstract: | Porous composites scaffolds of chitosan/poly(d,l-lactide-co-glycolide) were fabricated for tissue engineering applications by thermally induced phase separation and lyophilization techniques. The in vitro bioactivity evaluation of the scaffolds was carried out by analyzing the apatite layers produced on them using SBF as incubation medium. The apatite formation was analyzed using FTIR spectroscopy and Field emission scanning electron microscopy coupled to energy-dispersive electron X-ray spectroscopy. The cumulative results obtained from the IR spectra and SEM-EDS suggest that the developed composites might have potential applications in tissue engineering. |
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Keywords: | Bioactive materials Chitosan Poly( smallcaps" >d,l-lactide-co-glycolide) SBF |
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