| ~(131)I核素治疗Graves病对甲亢性糖尿病的影响及其相互关系的探讨 |
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| 引用本文： | 孔令华,王雪芹,吴俊渊,顾凯凯,高彬. ~(131)I核素治疗Graves病对甲亢性糖尿病的影响及其相互关系的探讨[J]. 化工之友, 2011, 0(23) |
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| 作者姓名： | 孔令华 王雪芹 吴俊渊 顾凯凯 高彬 |
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| 作者单位： | 南通大学第二附属医院核医学科; |
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| 摘 要： | 目的为了探讨131I核素治疗Graves病对甲亢合并糖尿病患者的影响并了解其相互关系。方法根据1999年WHO糖尿病诊断标准和Graves病诊断标准,排除其它相关影响因素,对69例甲亢合并糖尿病患者随机分组35例经ATD控制病情,在甲硫咪唑停药1周,丙基硫氧嘧啶停药至少2周后,行131I核素治疗;34例采用ATD治疗。分别于治疗后1、3、6个月进行TSH、FT3、FT4以及空腹血糖、餐后2h血糖的测定。Graves病疗效判定标准依次为治愈、好转、无效、甲减。糖尿病疗效评价标准分别为显效、好转、无效。结果 6个月131I核素治疗后复查35例患者Graves病治愈26例(74.29%),其中糖尿病有效25例(71.43%)、无效1例(2.86%);Graves病好转5例(14.29%),其中糖尿病有效5例(14.29%);Graves病无效0例;甲减4例(11.43%),其中糖尿病有效4例(11.43%)。Graves病治愈率为85.71%,糖尿病有效率为97.14%。6个月ATD治疗后复查34例患者Graves病治愈1例(2.94%),其中糖尿病有效1例(2.94%);Graves病好转26例(76.47%),...
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| 关 键 词： | 格雷夫斯病 糖尿病 放射疗法 碘放射性同位素 |
To Investigate the Relationships and Affects between Hyperthyroidism with Diabetes Mellitus and ~(131)I Radionuclide Therapy |
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| KONG Linghua WANG Xueqin WU Junyuan et al. To Investigate the Relationships and Affects between Hyperthyroidism with Diabetes Mellitus and ~(131)I Radionuclide Therapy[J]. Friend of Chemical Industry, 2011, 0(23) |
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| Authors: | KONG Linghua WANG Xueqin WU Junyuan et al |
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| Affiliation: | KONG Linghua WANG Xueqin WU Junyuan et al Department of Nuclear Medicine,the Second Affiliated Hospital of Nantong University,Jiang su 226001,China |
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| Abstract: | Objective To investigate the radionuclide 131I treatment of hyperthyroidism with Graves Disease on the impact of diabetes and to understand their relationship.Methods According to the 1999 WHO diagnostic criteria for diabetes and Graves disease diagnostic criteria,the exclusion of other relevant factors,69 patients with hyperthyroidism were randomly assigned 35 patients with diabetes control the disease by ATD,stopping in Methimazole week propylthiouracil at least 2 weeks after drug withdrawal,OK 131I radio... |
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| Keywords: | Graves'disease Diabetes mellitus Radiotherapy Iodine radioisotopes |
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