三七活性成分提取、分离纯化及其抗氧化活性研究进展

三七作为我国著名的中草药之一,拥有广泛的使用历史,是典型的药食两用品种。多项研究证实,三七活性成分具有降血脂、降血压、抗炎及增强免疫力等作用,主要以皂苷类、多糖类、黄酮类、三七素、氨基酸及挥发油等有效成分为代表,在生物医药、食品及保健品等领域具有良好的发展潜力和应用前景。随着提取、分离纯化技术的飞快发展,三七的研究得到国内外学者的广泛关注,不同的提取方法对三七中活性成分的结构有一定的影响,而结构与其功能特性密不可分。另有研究表明,三七具有较强的抗氧化活性,但其内在活性机制还有待进一步深入挖掘。因此,本文对三七中主要活性成分的提取、分离纯化方法及抗氧化活性进行综述,以明确三七活性成分提取、分离纯化工艺之间的异同对其活性的影响,从而为三七的进一步开发利用提供重要的理论参考。

Research progress on extraction, separation and purification, antioxidant activity of active components from Panax notoginseng

As one of the most well known Chinese herbal medicines in China, Panax notoginseng has a wide history of use, and is a typical variety for both medicinal and culinary purposes. There are numerous active constituents in Panax notoginseng, including saponins, polysaccharides, and flavonoids. Multiple studies have demonstrated that the active ingredient could alter blood lipids, lower blood pressure, promote anti-inflammatory activity, and boost immunity. Therefore, it can be a valuable factor with further application and development potential. As a result of the rapid development of extraction, isolation and purification technology, the study of Panax notoginseng has attracted a great deal of attention from academicians both domestically and internationally. Different extraction methods have a certain effect on the structure of the active ingredients in Panax notoginseng, which is inseparable from its functional properties. In addition, several studies have demonstrated that Panax notoginseng has a potent antioxidative effect, however, its intrinsic activity mechanism needs to be further explored in depth. Therefore, this paper reviewed the extraction and separation methods and antioxidant activities of the main active components in Panax notoginseng. Moreover, it discussed the antioxidative effect of active ingredients, in order to clarify the influence of the differences and similarities between the extraction, separation and purification processes of Panax notoginseng on its activities, so as to provide important theoretical references for the further development and utilization of Panax notoginseng.