生物医用可降解锌基合金的研究进展

锌基合金是近几年新兴的一种医用可降解材料,有望应用于心血管支架及骨植入等医疗器械。锌是人体必需的营养元素,具有良好的生物相容性及适宜的体内降解速率,作为可降解合金的基体有很广的应用前景。然而,生物可降解锌基合金的设计、加工、强化及降解机理等研究尚处于起步阶段,还需要做大量的基础研究工作。本文以最终医疗器械产品的理想标准要求为切入点,从生物相容性、力学性能及抗腐蚀性能等方面对近几年医用锌基合金的研究成果进行了综述分析,并展望了其未来的发展方向。

Research Progress on Biomedical Degradable Zinc-based Alloys

Zinc-based alloys are emerging medical degradable materials in recent years and are expected to be used in medical devices such as cardiovascular stents and bone implants. Zinc is an essential nutritional element of the human body, has good biocompatibility and suitable degradation rate in vivo, and has great potential to be a promising substrate for biodegradable alloys. However, the research on the design, processing, strengthening and degradation mechanism of biodegradable zinc-based alloys is still in its infancy, and a great deal of basic research is needed. In this paper, the biocompatibility, mechanical properties and corrosion resistance and other aspects of the research results of medical zinc-based alloys in recent years are reviewed based on the final standard of medical device products. The future research and development direction of zinc-based alloys are prospected as well.