Multi-Component HPLC Analysis and Antioxidant Activity Characterization of Extracts from Dipsacus sativus (Linn.) Honck |
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| Authors: | Bingxian Yang Xiao Feng Jinke Xu Houxing Lei |
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| Affiliation: | 1. Department of Biomedical Engineering, The Key Laboratory of Biomedical Engineering Ministry of Education, Zhejiang University, Hangzhou, China;2. Shandong Provincial Hospital, Jinan, China;3. Shandong Center for Disease Control and Prevention, Jinan, China;4. Lishui People’s Hospital, Lishui, China |
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| Abstract: | A highly reliable high-performance liquid chromatography method was developed and validated for determining quality of extracts from the leaves of Dipsacus sativus (Linn.) Honck. Under optimum conditions, the chromatography profile of eight compounds was collected, with compound saponarin as marker. The analysis results indicated that saponarin and isovitexin were the main active components. Pharmacological experiments proved that extracts from the leaves showed significant antioxidant activity. This work could serve to validate the usefulness of high-performance liquid chromatography analyses in traditional Chinese medicine. |
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| Keywords: | Dipsacus sativus (Linn.) Honck Isovitexin Saponarin SOD MDA |
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