化学计量学在海洛因分类中的应用

世界各国执法机构不断加强对毒品犯罪的打击力度,希望根除毒品的非法生产和贸易.为达到这一目的,通过对没收毒品的物理和化学分析可获得重要的信息,特别是与来源和生产有关的杂质的确证和定量,尤为重要.从这些数据中可获得各种有用的表征,即,杂质图谱(又称化学表征或指纹分析),用于比对分析以推断毒品的来源,化学计量学为比对分析的方法.鉴于目前使用了多种化学计量学方法,有必要对其进行分类整理.本文依据海洛因样品分类中所使用化学计量学方法的原理和应用进行了综述,以期化学计量学在海洛因样品分类中获得更好地应用.

Application of chemometrics in heroin source determination

All over the world,law enforcement agencies try to eradicate the illicit production and trafficking of drug.To this aim,im- portant information is obtained by physical and chemical toxicological analysis of drug seizures,with special attention for the identifica- tion and the quantification of minor component,such as the impurities related to the origin and manufacturing.In terms of these data, impurity profiles(chemical signatures or fingerprints)can be achieved and used for comparative analysis.In terms of the principle and application,this review focuses on data handling strategies,so called chemometrics,to produce these profiles for heroin comparison and origin determination.