Composition and antioxidant and antimicrobial activity of the essential oil and extracts of Stachys inflata Benth from Iran |
| |
Authors: | Abdolrasoul H Ebrahimabadi Ebrahim H Ebrahimabadi Zahra Djafari-Bidgoli Fereshteh Jookar Kashi Asma Mazoochi Hossein Batooli |
| |
Affiliation: | 1. Essential Oils Research Institute, University of Kashan, Post Code 87317-51167 Kashan, Islamic Republic of Iran;2. Isfahan Research Center of Natural Sources, Kashan Station, Kashan, Islamic Republic of Iran |
| |
Abstract: | Composition and antioxidant and antimicrobial activities of essential oil and methanol extract polar and nonpolar subfractions of Stachys inflata were determined. GC and GC/MS analyse of the essential oil showed 45 constituents representing 95.46% of the oil, the major components linalool (28.55%), α-terpineol (9.45%), spathulenol (8.37%) and (2E)-hexenal (4.62%) constituted 50.99% of it. Essential oil and extracts were also tested for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene/linoleic acid assays. In the DPPH test, IC50 value for the polar subfraction was 89.50 μg/ml, indicating an antioxidant potency of about 22% of that of butylated hydroxytoluene (IC50 = 19.72 μg/ml) for this extract. In β-carotene/linoleic acid assay, the best inhibition belonged to the nonpolar subfraction (77.08%). Total phenolic content of the polar and nonpolar extract subfractions was 5.4 and 2.8% (w/w), respectively. The plant also showed a week antimicrobial activity against three strains of tested microorganisms. Linalool and α-terpineol were also tested as major components of the oil and showed no antioxidant but considerable antimicrobial activities. |
| |
Keywords: | Stachys inflata Essential oil Extract Antioxidant activity Antimicrobial activity Linalool α-Terpineol Total phenolic |
本文献已被 ScienceDirect 等数据库收录! |
|