Electric and magnetic fields of the brain accompanying internal simulation of movement |
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Authors: | W Lang D Cheyne P H?llinger W Gerschlager G Lindinger |
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Affiliation: | ZENECA Pharmaceuticals, Department of Infection Research, Alderly Park, Macclesfield, UK. |
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Abstract: | We show that the antibacterial agent, (6S)-6-fluoroshikimate, is a substrate for the shikimate transport system of Escherichia coli because in exchange-diffusion experiments it displaced intracellular 14C]shikimate with the same kinetics as did unlabelled shikimate. Other shikimate analogues were also substrates: as judged by similar experiments or, in the case of (6R)-6-fluoroshikimate, by inference. |
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