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Inverted-U Function Between Salivary Cortisol and Retrieval of Verbal Memory After Hydrocortisone Treatment.
Authors:Domes  Gregor; Rothfischer  Julia; Reichwald  Ursula; Hautzinger  Martin
Abstract:The present study investigated the effect of a single oral dose of hydrocortisone (cortisol) on retrieval of verbal and nonverbal declarative memory. Fifty-nine healthy participants were randomly assigned to either receive 25 mg cortisol or a placebo 45 min before retrieval in a standardized memory test procedure. There was no global effect of cortisol on either verbal or nonverbal memory. However, a specific negative effect on free recall of associative verbal material appeared. In addition, high responders (salivary cortisol concentration > 68.25 nmol/L) exhibited impaired verbal memory compared with low responders (
Keywords:salivary cortisol  verbal & nonverbal declarative memory  hydrocortisone  cortisol  glucocorticoids  human sex differences
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