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流感病毒的演变传播及抗病毒药物和疫苗的研究进展
引用本文:陈执中.流感病毒的演变传播及抗病毒药物和疫苗的研究进展[J].食品与药品,2009,11(3).
作者姓名:陈执中
作者单位:复旦大学药学院,上海,201203
摘    要:流感病毒是引起人类流感的传染性病毒.1918年流感风暴席卷全球,至今仍为挥之不去的梦魇.本文综述了流感病毒的演变,在世界的传播路线和流感病毒"劫持"人体细胞的新机制,以及抗流感病毒新药和新型流感疫苗的研究进展.神经氨酸苷酶抑制剂的应用和新型流感疫苗的研制成功将为预防和治疗流感开拓广阔的前景.

关 键 词:流感病毒  演变和传播  神经氨酸苷酶抑制剂  新型疫苗

Evolution and Spread of Influenza Virus and Progress on Antiviral Drugs and Vaccines
CHEN Zhi-zhong.Evolution and Spread of Influenza Virus and Progress on Antiviral Drugs and Vaccines[J].Food and Drug,2009,11(3).
Authors:CHEN Zhi-zhong
Abstract:The influenza virus is an infectious virus in mankind. After the storm of influenza across the world in 1918, that is nightmare incessantly now. In this article, the evolution and spread of itinerary map of influenza virus are reviewed. Additionally, the progress on unique 'cap-snatching' mechanism, antiviral drugs and vaccines are also introduced. The applications of neuraminidase inhibitors and the developments of new influenza vaccines will open up broad prospects for the prevention and therapy of influenza.
Keywords:influenza virus  evolution and spread  neuraminidase inhibitor  new vaccine
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