环境中五氯酚对水生生物的毒理学研究进展

:五氯酚（PCP）在生产和生活中常被用作杀虫剂、抗菌剂和防腐剂，会大量地富集在沉积物和生物体内。PCP 具有极高的毒性，在环境中难降解，持久性长，其大量使用和不恰当处理，将造成水体严重污染。因此，PCP 在水环境中的生态毒理效应一直是人们关注的热点。总结了近几年PCP 对水生生物毒理学研究，主要包括对水生生物的氧化损伤、急性毒性、内分泌干扰、遗传毒性、细胞毒性及发育毒性等的效应和机制，同时，关于PCP 对水生生物的毒性效应进一步的研究进行了展望。

Recent Research Progress in Toxicological Effects of Pentachlorophenol on Aquatic Organisms

Pentachlorophenol （PCP） is often used as insecticide， antiseptic and preservative in indurstry and daily life， and will be abundantly accumulated in sediments and organisms. PCP has extremely high toxicity，which degrades slowly in the environment and persists for many years. Its extensive usage and improper treatment can cause serious water pollution. Therefore， the ecotoxicological effect of PCP in the water environment has been a hot spot， drawing much attention. This paper summarizes the recent studies on the toxicological effects of PCP on aquatic organisms， including the effects and mechanisms of oxidative damage， acute toxicity， endocrine disruption， genotoxicity， cytotoxicity and developmental toxicity on aquatic organisms. Moreover，the further study on the toxicological effects of PCP is also prospected.