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四株狂犬病街毒的免疫学特性
引用本文:吴杰,徐葛林,郑新雄,吴泰才,朱家鸿.四株狂犬病街毒的免疫学特性[J].粉末涂料与涂装,2002,15(2):81-82.
作者姓名:吴杰  徐葛林  郑新雄  吴泰才  朱家鸿
作者单位:武汉生物制品研究所,武汉生物制品研究所,武汉生物制品研究所,武汉生物制品研究所,武汉生物制品研究所 武汉430060,武汉430060,武汉430060,武汉430060,武汉430060
摘    要:目的 研究国内分离的4株狂犬病街毒的免疫学特性。方法 采用免疫力试验及中和试验进行抗原性及免疫原性检测。结果4株街毒抗原性存在一定差异,应用aG株疫苗免疫小鼠能保护4株街毒的攻击。结论aG疫苗与4株街毒具有良好的交叉免疫性。

关 键 词:狂犬病  街毒  抗原性  免疫原性
修稿时间:2001年4月30日

Immunological Characteristics of 4 Rabies Street Virus Strains
WU Jie,XU Gelin,ZHENG Xinxiong et al.Immunological Characteristics of 4 Rabies Street Virus Strains[J].Chinese Journal of Biologicals,2002,15(2):81-82.
Authors:WU Jie  XU Gelin  ZHENG Xinxiong
Abstract:Abstract] Objective To study on the immunological characteristics of 4 rabies street virus strains isolated in China. Methods The antigenicities and immunogenicities of the 4 strains were detected by immunity and neutralizing tests. Results Significant difference were observed in the antigeinicities of the 4 strains. However, the vaccine prepared with aG strain could protect mice against the challenge with the 4 street virus strains. Conclusion aG vaccine showed good cross immunity to the 4 street virus strains.
Keywords:Rabies Stree virus  Antigenicity  Immunogenicity
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