| 抗菌高分子材料研究进展及应对策略 |
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| 引用本文： | 谢辉,向书永,朱才镇,徐坚.抗菌高分子材料研究进展及应对策略[J].高分子材料科学与工程,2021,37(2):149-156. |
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| 作者姓名： | 谢辉 向书永 朱才镇 徐坚 |
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| 作者单位： | 深圳大学化学与环境工程学院 低维材料基因工程研究院,广东 深圳 518060 |
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| 基金项目： | 国家自然科学基金资助项目(51673117,51973118);深圳市科学技术创新委员会(JCYJ20170818093832350,JCYJ20170818112409808,JSGG20170824112840518,JCYJ20180507184711069,JCYJ20170818100112531,JCYJ20170817094628397,JCYJ20180305125319991);广东省重点领域研究开发计划(2019B010929002,2019B010941001)。 |
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| 摘 要： | 日常生活中细菌感染极易引起人类的健康问题,因此开发更高效的抗菌材料以减小感染带来的风险,具有重要的科学意义和应用价值。其中,抗菌高分子材料由于具有良好的生物相容性、抗菌持久性、不易使细菌产生耐药性,同时其品种丰富、合成和改性相对简单,是当前抗菌材料研究的热点。根据抗菌高分子材料的最新发展趋势,文中着重介绍了阳离子抗菌材料、共轭高分子抗菌材料和抗菌肽等重要高分子抗菌材料,阐述了其抗菌机制,以各种材料的结构、性能、应用之间的关系为主线,总结了抗菌高分子材料的研究进展并展望了其未来发展方向。
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| 关 键 词： | 细菌感染 抗菌活性 高分子抗菌材料 抗菌机制 |
Progress and Countermeasures of Antibacterial Polymer Materials |
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| Hui Xie,Shuyong Xiang,Caizhen Zhu,Jian Xu.Progress and Countermeasures of Antibacterial Polymer Materials[J].Polymer Materials Science & Engineering,2021,37(2):149-156. |
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| Authors: | Hui Xie Shuyong Xiang Caizhen Zhu Jian Xu |
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| Affiliation: | (School of Chemistry and Environmental Engineering,Shenzhen University,Institute of Genetic Engineering for Low Dimensional Materials,Shenzhen 518060,China) |
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| Abstract: | Bacterial infections in daily live have posed serious threats to human health,and thus,the development of more efficient antibacterial materials to reduce the risk of infection has important scientific significance and application value.Among different kinds of materials,antibacterial polymer materials are the current research hotspots since they have good biocompatibility,antibacterial durability,and are not easy to cause bacteria to develop drug resistance.They also have abundant varieties,relatively simple synthesis and modification processes.This review focused on four trending polymer antibacterial materials including chitosan and its derivatives,cationic antibacterial polymers,conjugated polymers,and antibacterial peptides.Each material antibacterial mechanism was explained as well.Based on the relationship among structures,performance,and applications,this review summarized the most recent research on antibacterial polymer materials and looked forward to some potential development directions. |
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| Keywords: | bacterial infections antibacterial activity antibacterial polymer material antibacterial mechanism |
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