| 基于酶和无机/金属纳米颗粒组装的生物复合催化剂 |
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| 引用本文： | 宗璟,陈英文,祝社民,王安明,沈树宝,欧阳平凯.基于酶和无机/金属纳米颗粒组装的生物复合催化剂[J].化工学报,2006,57(8):1776-1781. |
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| 作者姓名： | 宗璟 陈英文 祝社民 王安明 沈树宝 欧阳平凯 |
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| 作者单位： | 南京工业大学制药与生命科学学院;南京工业大学材料科学与工程学院,江苏,南京,210009 |
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| 基金项目： | 中国科学院资助项目
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江苏省自然科学基金
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江苏省社会发展基金 |
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| 摘 要： | 综述了具有生物兼容性的无机/金属纳米颗粒和酶组装成生物复合催化剂的最新进展，并从纳米材料的自身特性出发，分析了酶和无机/金属纳米颗粒组装的多种方法以及纳米粒子在多个方面对酶催化效率的影响，进而归纳了纳米颗粒对酶具有的多种纳米载体效应.最后探讨并展望了利用酶和无机/金属纳米颗粒的组装将天然酶改造成更高效的复合生物催化剂的研究现状与前景.
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| 关 键 词： | 酶 纳米颗粒 组装 生物杂合体 纳米载体效应 |
| 文章编号： | 0438-1157（2006）08-1776-06 |
| 收稿时间： | 12 26 2005 12:00AM |
| 修稿时间： | 2005-12-262006-04-11 |
Complex biocatalysts assembled by enzymes and inorganic/metal nanoparticles |
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| ZONG Jing,CHEN Yingwen,ZHU Shemin,WANG Anming,SHEN Shubao,OUYANG Pingkai.Complex biocatalysts assembled by enzymes and inorganic/metal nanoparticles[J].Journal of Chemical Industry and Engineering(China),2006,57(8):1776-1781. |
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| Authors: | ZONG Jing CHEN Yingwen ZHU Shemin WANG Anming SHEN Shubao OUYANG Pingkai |
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| Affiliation: | 1.School of Life Science and Pharmacy ; 2.School of Material Science and Engineering, Nanjing University of Technology, Nanjing 210009, Jiangsu, China |
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| Abstract: | The recent progress in complex biocatalysts assembled by biocompatible inorganic/metal nanoparticles and enzymes is reviewed. The assembly methods and the effects of nanoparticles on the catalytic activity and efficiency of enzymes are analyzed by taking account of the properties of nanomaterials. Furthermore, several nanoparticle-carrier effects on enzymes are summarized. Finally, the status of converting native enzymes to highly efficient conjugating biocatalysts by assembling enzymes and inorganic/metal nanoparticles is discussed, and the prospective application is also forecasted. |
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| Keywords: | enzyme nanoparticle assemble bioconjugate nanoparticle-carrier effects |
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