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The Innate Immune-Related Genes in Catfish
Authors:Lei Gao  Chongbo He  Xueguang Liu  Hao Su  Xianggang Gao  Yunfeng Li  Weidong Liu
Affiliation:1.Liaoning Ocean and Fisheries Science Research Institute, Dalian 116023, China; E-Mails: (L.G.); (H.S.); (X.G.); (Y.L.); (W.L.);2.Key Laboratory of Marine Fishery Molecular Biology of Liaoning Province, Dalian 116023, China;3.Liaoning Fisheries Technology Extension Station, Shenyang 110031, China; E-Mail:
Abstract:Catfish is one of the most important aquaculture species in America (as well as in Asia and Africa). In recent years, the production of catfish has suffered massive financial losses due to pathogen spread and breakouts. Innate immunity plays a crucial role in increasing resistance to pathogenic organisms and has generated increasing interest in the past few years. This review summarizes the current understanding of innate immune-related genes in catfish, including pattern recognition receptors, antimicrobial peptides, complements, lectins, cytokines, transferrin and gene expression profiling using microarrays and next generation sequencing technologies. This review will benefit the understanding of innate immune system in catfish and further efforts in studying the innate immune-related genes in fish.
Keywords:catfish   channel catfish (Ictalurus punctatus)   innate immunity   antimicrobial peptide   complement   lectin   cytokine   RNA-seq   gene expression profiling
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