Imidazolium triflate as an efficient promoter for O-selective phosphitylation of N-unprotected nucleosides via the phosphoramidite approach |
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| Authors: | M Kataoka S Heidenhain Y Hayakawa |
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| Affiliation: | Laboratory of Bioorganic Chemistry, Graduate School of Human Informatics, Nagoya University, Japan. |
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| Abstract: | A novel method for the preparation of nucleotides via the phosphoramidite approach with imidazolium triflate 1 as a promoter has been developed. This approach required no protecting groups for nucleoside bases of building blocks. |
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