D-核糖发酵液电渗析脱盐及工艺优化

D--核糖发酵液中残存着大量的无机离子，如不去除会影响后续D--核糖的纯化。目前工业上常采用离子交换树脂脱盐，随着料液含盐量的增加，其脱盐成本也成比例增加，并产生大量的废水，既不经济也不环保。为明确电渗析脱盐是否可行、具体脱盐成本及最佳的脱盐工艺，以D-D-核糖发酵液的滤液为原料，采用均相阳离子交换膜CMX和阴离子交换膜AMX组成的小试设备LANRAN-40-2040，进行了电渗析法脱盐研究。结果表明，将脱盐率控制在54%，产品收率达到97.68%，但当进一步提高脱盐率时，会有一定量的D--核糖渗透到电渗析浓缩室中，且随着运行时间的增加，浓缩室的D--核糖质量浓度增加较快。采用电渗析联合离子交换树脂脱盐工艺比全树脂脱盐工艺产品收率提高了1.9%，节约一半的离子交换树脂及酸碱用量，并减少一半的废水排放，因此为D--核糖的工业生产提供较好的参考。

Desalination and Process Optimization of D--Ribose Fermentation Broth by Electrodialysis

There are a large number of inorganic ions in D--ribose fermentation broth, which will affect the subsequent purification of D--ribose if not removed. At present, ion exchange resins are often adopted for desalination in industry. The cost of desalination increases proportionally with the increase of feed liquid salt content, and generates a large amount of wastewater, which is neither economical nor environmentally friendly. In order to determine the feasibility of electrodialysis desalination, the specific cost of desalination and the best desalination process, the desalting experiment of electrodialysis was carried out with the filtrate of D--ribose fermentation broth as the raw material and Lanran-40-2040 composed of homogeneous cation exchange membrane CMX and anion exchange membrane AMX as the laboratory-scale equipment. The results showed that when the desalination rate was controlled at 54%, the product yield reached 97.68%. However, when the desalination rate was further increased, a certain amount of D--ribose would permeate into the electrodialysis concentration chamber, and the D--ribose content in the concentration chamber increased rapidly with the increase of operation time. Compared with the whole resin desalination process, the product yield of electrodialysis combined with ion exchange resin desalination process was increased by 1.9%, which saved half of the ion exchange resin, acid and alkali, and reduced half of the wastewater discharge. Therefore, this study could provide a good reference for the industrial production ofD--ribose.