| 神经病理性疼痛的药物治疗研究进展 |
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| 引用本文： | 李招胜,林洪,沙漠,丁真奇.神经病理性疼痛的药物治疗研究进展[J].金属学报,2013,18(9):1076-1080. |
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| 作者姓名： | 李招胜 林洪 沙漠 丁真奇 |
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| 作者单位： | 1.中国人民解放军第一七五医院,漳州 363000,福建;2.南昌大学医学院,南昌 330000,江西 |
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| 摘 要： | 神经病理性疼痛是一种神经系统损伤引起的慢性疼痛,严重影响患者的生活质量。药物治疗仍是现用治疗神经病理性疼痛的主要方法。本文综述了现用于治疗神经病理性疼痛主要药物的分子药理机制及其临床运用特点,并在总结疼痛的发生机制的基础上对靶向治疗药物的研发进行了展望。
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| 关 键 词： | 神经病理性疼痛 药物治疗 镇痛 综述 |
| 收稿时间： | 2013-02-04 |
| 修稿时间： | 2013-07-17 |
Update in the pharmacotherapy for neuropathic pain treatment |
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| LI Zhao-sheng,LIN Hong,SHA Mo,DING Zhen-qi.Update in the pharmacotherapy for neuropathic pain treatment[J].Acta Metallurgica Sinica,2013,18(9):1076-1080. |
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| Authors: | LI Zhao-sheng LIN Hong SHA Mo DING Zhen-qi |
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| Affiliation: | 1.The 175th Hospital of PLA, Zhangzhou 363000, Fujian,China;2.Medical College of Nanchang University, Nanchang 330000, Jiangxi,China |
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| Abstract: | Neuropathic pain is a form of chronic pain caused by nervous lesions and significantly reduces patients' quality of life. Nowadays pharmacotherapy is still the main therapeutic paradigm. The article summarizes the underlying molecular pharmacologic mechanisms of the drugs used in the pharmacotherapy as well as their application characteristics in the clinical practice, and points out the perspective of the development of targeted drugs on the basis of elucidating the mechanisms of neuropathic pain. |
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| Keywords: | Neuropathic Pain Pharmacotherapy Analgesic Review |
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