| 药片崩解剂羧甲基淀粉的合成 |
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| 引用本文： | 吾国强,吴雪妹,吕延文,吕亮,金昭华.药片崩解剂羧甲基淀粉的合成[J].精细化工,1999,16(4). |
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| 作者姓名： | 吾国强 吴雪妹 吕延文 吕亮 金昭华 |
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| 作者单位： | 浙江工业大学,浙西分校,化工系,浙江,衢州,324006 |
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| 摘 要： | 以马铃薯淀粉为原料，采用交联、醚化复合变性方法合成羧甲基淀粉，产品在常温下能快速吸水膨胀而不糊化，适用于药片崩解剂。最佳投料量：淀粉３０ｇ，氯乙酸５．０ｇ，氢氧化钠４．５ｇ，环氧氯丙烷４．８ｍｌ。
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| 关 键 词： | 崩解剂 淀粉 羧甲基淀粉 交联淀粉 |
| 文章编号： | 1003-5214(1999)04-0004-03 |
| 修稿时间： | 1998－06－25 |
Synthesis of Tablets Disintegrant Carboxymethyl Starch |
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| WU Guo-qiang,WU Xue-mei,L Yan-wen,L Liang,JIN Zhao-hua.Synthesis of Tablets Disintegrant Carboxymethyl Starch[J].Fine Chemicals,1999,16(4). |
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| Authors: | WU Guo-qiang WU Xue-mei L Yan-wen L Liang JIN Zhao-hua |
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| Affiliation: | WU Guo-qiang,WU Xue-mei,L(U) Yan-wen,L(U) Liang,JIN Zhao-hua |
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| Abstract: | Crosslinked,etherified potato starches which are capable of swelling but not gelatinized in cold water were prepared.The products can be used as tablets disintegrant.The disintegrants have the best disintegrating performance when the reaction coditions were:30g starch,5.0g chloroacetic acid,4.5g sodium hydroxide,4.8ml epichlorohydrin. |
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| Keywords: | disintegrant starch carboxymethyl starch crosslinked starch |
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