| Abstract: | Abstract Rhenium-188 is a radionuclide with favorable physical characteristics suitable for radiotherapeutic purposes (T1/2 16.9 h, Eβmax 2.12 MeV; Eγ 155 keV (15%)) for radiotherapeutic purposes and can be continually obtained from 188W/188Re generator systems. The preparation conditions of an alumina based 188W/188Re generator are reported. Initially, the W and Re sorption behavior on alumina in NaCl and HCl medium was performed evaluating the following parameters: medium pH, alumina size particle, sorption capacity, and kinetic. Re-188 is not adsorbed in HCl and NaCl medium whereas W-188 is strongly adsorbed in both media at pH < 5. The strongest sorption of W was obtained in alumina with a particle size of 0.075–0.048 mm. The weight capacity of alumina is approximately 0.337 meq/g and the sorption equilibrium in static conditions is attained after 18 hours. This data was used to construct and evaluate alumina 188W/188Re-generators for a period of six months. |
