Abstract: | A novel separation method based on micelle-mediated extraction and cloud-point preconcentration was developed for the hydrophobic compounds of psoralen and isopsoralen from Psoralea corylifolia L. by high performance liquid chromatography with photodiode array detection. The GENAPOL X080 was chosen as the extract surfactant. A series of experimental conditions were probed to optimize the extraction and preconcentration process. The optimized technique is a cheap, simple, and sensitive method. |