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Complementary PCAF–Coenzyme A Mutagenesis: Chemoenzymatic Synthesis of a Novel Enlarged Coenzyme A Analogue and Evaluation of Its Biological Activity
Authors:Dr Leang Khim  Dr Juan Han  Dr Lynsey Willetts  Dr Kevin Brady  Dr Pauline Gillece  Ouannassa Rached  Prof Dr Neil R Thomas  Dr Eleni Stylianou
Affiliation:1. University of Nottingham, School of Biomedical Sciences, Queen's Medical Centre, Nottingham, NG7 2UH (UK);2. University of Nottingham, School of Chemistry, Centre for Biomolecular Sciences, University Park, Nottingham, NG7 2RD (UK), Fax: (+44)?115‐951‐3564;3. Cleveland Clinic Foundation, Lerner Research Institute, Department of Pathobiology, 9500 Euclid Avenue, Cleveland, Ohio 44195 (USA), Phone: (+1)?216‐445‐7156
Abstract:
Keywords:acetyl‐coenzyme A  DPCK  enzymes  PCAF  PPAT  transferases
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