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In Silico Characterization of Ligand Binding Modes in the Human Histamine H4 Receptor and their Impact on Receptor Activation
Authors:Tim Werner  Kerstin Sander  Yusuf Tanrikulu Dr  Tim Kottke  Ewgenij Proschak Dr  Holger Stark Prof Dr  Gisbert Schneider Prof Dr
Affiliation:1. Formerly: Institute of Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe‐University Frankfurt/Main, Siesmayerstrasse 70, 60323 Frankfurt/Main (Germany);2. Institute of Pharmaceutical Chemistry, ZAFES/LiFF/CMP/ICNF, Johann Wolfgang Goethe‐University Frankfurt/Main, Max‐von‐Laue‐Strasse 9, 60438 Frankfurt/Main (Germany);3. ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Wolfgang‐Pauli‐Strasse 10, 8093 Zürich (Switzerland), Fax: (+41)?44‐633‐13‐79
Abstract:
Keywords:G protein‐coupled receptors  histamine receptors  molecular dynamics  proteins
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