Synthesis of 1,4-dihydropyridine derivatives using nanocrystalline copper(II) oxide catalyst |
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| Authors: | M. Lakshmi Kantam T. Ramani L. Chakrapani B.M. Choudary |
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| Affiliation: | 1. Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500007, India;2. Ogene Systems (I) Pvt. Ltd., No. 11-6-56, GSR Estates, Moosapet, Hyderabad 500037, India |
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| Abstract: | Nanocrystalline copper(II) oxide catalyzed three-component coupling of aromatic amines, β-ketoesters and cinnamaldehyde to afford the corresponding 1,4-dihydropyridines in moderate to good yields under mild conditions is described. The catalyst can be recovered and reused for four cycles with almost consistent activity. |
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