| 富马酸二甲酯的合成工艺研究 |
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| 引用本文： | 赵瑞华,张建伟,衣守志.富马酸二甲酯的合成工艺研究[J].应用化工,2004,33(3):36-38. |
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| 作者姓名： | 赵瑞华 张建伟 衣守志 |
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| 作者单位： | 天津科技大学,材料科学化学工程学院,天津,300222 |
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| 摘 要： | 以马来酸酐和甲醇为原料,用磷钨酸作酯化催化剂制得马来酸二甲酯,再用硫脲作异构化催化剂制得富马酸二甲酯。通过正交实验确定出最佳工艺条件为:甲醇∶马来酸酐的摩尔比为8∶1,催化剂磷钨酸的用量是马来酸酐用量的10%,酯化时间为5h,催化剂硫脲用量为马来酸酐用量的2.5%,异构化时间为20～30min,产率可达87.8%。
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| 关 键 词： | 顺酐 磷钨酸 富马酸二甲酯 酯化 异构化 |
| 文章编号： | 1671-3206(2004)03-0036-03 |
| 修稿时间： | 2003年10月14 |
Study on synthesis technology of dimethyl fumarate |
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| ZHAO Rui-hua,ZHANG Jian-wei,YI Shou-zhi.Study on synthesis technology of dimethyl fumarate[J].Applied chemical industry,2004,33(3):36-38. |
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| Authors: | ZHAO Rui-hua ZHANG Jian-wei YI Shou-zhi |
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| Abstract: | Dimethyl fumarate was prepared from maleic anhydride and methanol with phospho-tungstic acid as the esterification catalyst and thiourea as the isomerization catalyst. The optimum condition were obtained. The molar ratio of methanol and maleic anhydride was 8∶1,the mass of phospho tungstic acid was 10% of maleic anhydride, esterification time was 5 h. The mass of isomerization catalyst was 2.5% of the mass of maleic anhydride and the isomerization time was 20～30 minutes. The rate of production was up to 87.8%. |
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| Keywords: | maleic anhydride phospho tungstic acid dimethyl fumarate esterification isomerization |
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