Green Synthesis of Silver Nanoparticles Using Salacia chinensis: Characterization and its Antibacterial Activity |
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Authors: | Kiran Jadhav Dinesh Dhamecha Bhagyashree Dalvi |
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Affiliation: | 1. KLE University's College of Pharmacy, Belgaum, Karnataka, India;2. Department of Pharmaceutical Science and Technology, Institute of Chemical Technology, Mumbai, Maharashtra, India |
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Abstract: | The aim of the present research work was to synthesize silver nanoparticles (AgNPs) using Salacia chinensis plant extract and to evaluate its antibacterial activity. AgNPs were successfully synthesized and formation of AgNPs was confirmed by visual color change and UV (ultraviolet) spectroscopy. Prepared AgNPs were purified and characterized by using dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, x-ray diffraction (XRD), scanning electron microscopy coupled with energy dispersive x-ray spectroscopy (SEM-EDAX), and transmission electron microscopy (TEM). UV peak at 434 nm confirmed the formation of AgNPs. DLS studies showed that AgNPs size prepared in all conditions were in the range of 100–200 nm. XRD studies revealed crystalline nature of AgNPs. EDAX studies confirmed the presence of silver in colloidal dispersion and images were recorded by using SEM and TEM. Synthesized AgNPs were found to be effective against Staphylococcus aureus and Pseudomonas aeruginosa. In conclusion, AgNPs could serve as a good alternative in treatment of bacterial infections in this era of multidrug resistance. |
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Keywords: | antibacterial activity antioxidants characterization green synthesis salacia chinensis silver nanoparticles |
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