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The Effects of Different Cranial Modules on Mechanical Properties of Cranial Suture in Lewis Rats and Same-aged C57BL/6 Mice |
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| Authors: | C. H. Chien Y. D. Wu Y. J. Chao T. Chen W. F. Chen J. C. Yu X. Li |
| Affiliation: | Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan, ROC; Metal Industries Research &Development Centre, Kaohsiung 81160, Taiwan, ROC; Department of Mechanical Engineering, University of South Carolina, Columbia, SC 29208, USA; Department of Electrical Engineering Fortune Institute of Technology, Kaohsiung 83160, Taiwan, ROC; Department of Surgery, Medical College of Georgia, Augusta, GA 30912, USA |
| Abstract: | Abstract: In this study we aimed at investigating size effects on mechanical properties of cranial suture in different animal research models. Lewis rats and C57BL/6 mice were selected as the larger research model and smaller research model, respectively. The objective of this study was to determine the mechanical properties of different cranial modules of cranial sutures in Lewis rats and same-aged C57BL/6 mice. Ten sagittal sutures were harvested from 4-month-old Lewis rats and C57BL/6 mice. The specimens, kept moist, were mounted fresh and distracted until rupture. A load–displacement curve was constructed. The stiffness, Young's modulus, fracture stress and fracture energy were calculated. Moreover, scanning electron microscope (SEM) images and fracture mechanisms are discussed. Cranial modules in Lewis rats and same-aged C57BL/6 mice are also provided. The results show differences between the two groups, with higher values from Lewis rat. Higher mechanical properties occurred mainly on the large type of cranial module in this mammalian system. |
| Keywords: | C57BL/6 mouse cranial module cranial suture Lewis rat mechanical property |