Evaluation of a commercial PCR kit for diagnosis of cytomegalovirus infection of the central nervous system |
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| Authors: | A Weinberg D Spiers GY Cai CM Long R Sun V Tevere |
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| Affiliation: | Pediatric Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USA. adriana.weinberg@uchsch.edu |
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| Abstract: | We evaluated the AMPLICOR cytomegalovirus (CMV) PCR kit for the diagnosis of neurologic CMV infections on 43 positive and 112 negative archived cerebrospinal fluid specimens originally tested by an in-house PCR method. The AMPLICOR kit showed sensitivity and specificity of 95 and 100%, respectively, versus the home-grown assay, indicating its utility in this clinical setting. |
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