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基于C-V模型的脑白质疏松症磁共振图像病变区域分割
引用本文:郑兴华,杨勇,张雯,朱英俊,徐伟栋,楼敏.基于C-V模型的脑白质疏松症磁共振图像病变区域分割[J].计算机应用,2011,31(10):2757-2759.
作者姓名:郑兴华  杨勇  张雯  朱英俊  徐伟栋  楼敏
作者单位:1.杭州电子科技大学 自动化学院, 杭州 310018 2.杭州电子科技大学 生命信息与仪器工程学院, 杭州 310018 3.浙江大学医学院 附属第二医院, 杭州 310007
基金项目:国家自然科学基金资助项目(30770685;81070915);浙江省重大科技专项(优先主题)国际科技合作项目(2008C14078)
摘    要:针对脑白质疏松症病变区域在磁共振图像的T2加权像上呈现斑块状或融合成片状的高亮信号这一特点,提出了一种基于C-V模型的水平集分割方法对病变区域进行图像分割。首先,对C-V模型进行改进以避免重新初始化问题;然后,使用Otsu阈值法对图像进行预分割,将预分割的结果直接作为改进C-V模型的初始轮廓;最后,利用水平集方法进行曲线演化,得到最终的分割轮廓。实验结果表明,该方法能较为准确地分割出病变区域,实现病变区域的计算机自动快速分割,对脑白质疏松症临床辅助诊断和预后判断有一定的应用价值。

关 键 词:脑白质疏松症  磁共振  C-V模型  水平集  Otsu阈值法  
收稿时间:2011-04-19
修稿时间:2011-06-07

Lesion area segmentation in leukoaraiosis's magnetic resonance image based on C-V model
ZHENG Xing-hua,YANG Yong,ZHANG Wen,ZHU Ying-jun,XU Wei-dong,LOU Min.Lesion area segmentation in leukoaraiosis's magnetic resonance image based on C-V model[J].journal of Computer Applications,2011,31(10):2757-2759.
Authors:ZHENG Xing-hua  YANG Yong  ZHANG Wen  ZHU Ying-jun  XU Wei-dong  LOU Min
Affiliation:1.College of Automation, Hangzhou Dianzi University, Hangzhou Zhejiang 310018, China
2.College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou Zhejiang 310018, China
3.Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou Zhejiang 310007, China
Abstract:Concerning that the lesion areas of leukoaraiosis in Magnetic Resonance (MR) image present hyper intense signal on T2 flair sequence, a level set segmentation method based on C-V model was proposed. First, the C-V model was improved to avoid the re-initialization; second, the Otsu threshold method was used for image's pre-segmentation, and then the image's pre-segmentation result was directly used as the initial contour for the improved C-V model; finally, the segmentation result was obtained by curve evolution. The results show that the proposed segmentation method can get better separation effects, and realize fast auto-segmentation. It has certain application value for clinical diagnosis and prognosis on leukoaraiosis.
Keywords:leukoaraiosis                                                                                                                          Magnetic Resonance (MR)                                                                                                                          C-V model                                                                                                                          level set                                                                                                                          Otsu threshold method
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