| 近红外光谱在中药大黄乙醇提取液快速分析中的应用研究 |
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| 引用本文： | 耿炤,胡浩武,李胜华,屈战果,王木兰,梅玲华.近红外光谱在中药大黄乙醇提取液快速分析中的应用研究[J].应用化工,2011,40(5). |
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| 作者姓名： | 耿炤 胡浩武 李胜华 屈战果 王木兰 梅玲华 |
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| 作者单位： | 江西汇仁药业有限公司,江西南昌,330052 |
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| 基金项目： | "重大新药创制"科技重大专项 |
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| 摘 要： | 用声光可调滤光器(AOTF)-近红外(NIR)光谱法在线分析中药大黄乙醇提取液比重及大黄素含量,用偏最小二乘(PLS1)法分别建立NIR光谱与含量、比重的校正模型。结果表明,提取液NIR光谱与比重、含量的校正模型相关系数R2分别为0.989 0,0.988 4,相对偏差分别为0.26%,2.66%,精密度分别为0.15%,2.84%;5 h稳定性分别为0.13%,2.03%,回收率分别为99.8%,95.6%。该方法具有快速、直接、多成分同时测定特点,并能实现现场在线分析。
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| 关 键 词： | 大黄素 AOTF近红外光谱 比重 在线分析 |
Study on analysis of Dahuang ethanol extract liquid with NIR spectroscopy |
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| GENG Zhao,HU Hao-wu,LI Sheng-hua,QU Zhan-guo,WANG Mu-lan,MEI Ling-hua.Study on analysis of Dahuang ethanol extract liquid with NIR spectroscopy[J].Applied chemical industry,2011,40(5). |
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| Authors: | GENG Zhao HU Hao-wu LI Sheng-hua QU Zhan-guo WANG Mu-lan MEI Ling-hua |
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| Affiliation: | GENG Zhao,HU Hao-wu,LI Sheng-hua,QU Zhan-guo,WANG Mu-lan,MEI Ling-hua(Jiangxi Huiren Pharmaceutical Co.,Ltd.,Nanchang 330052,China) |
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| Abstract: | A method for online analysis of specific density and emodin content of Dahuang ethanol extract fluid with acousto-optic-tunable-filter(AOTF)-near infrared(NIR) spectroscopy technology was established.The calibration model of NIR spectroscopy-specific density,and NIR spectroscopy-emodin content were established with partial least squares(PLS 1).Results showed that proportion of the data correlation between the calibration model coefficients R2 were 0.989 0 and 0.988 4,the average relative deviation were 0.26... |
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| Keywords: | emodin AOTF-NIR spectroscopy specific density on-site analysis |
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