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Mercury porosimetry in pharmaceutical technology
Authors:P.J. Dees  J. Polderman
Affiliation:Central Laboratory of the N.R.C. Blood Transfusion Service, Plesman Loan 125, 1006 AD Amsterdam The Netherlands;State University of Leyden, Department of Pharmaceutical Technology, Gorlaeus Laboratories, P. O. Box 9502, 2300 RA Leyden The Netherlands
Abstract:The literature on the use of mercury porosimetry in pharmaceutical technology is reviewed. The relation between the application and the preferable pore size distribution presentation is also discussed. In addition, pore size distributions of lactose tablets are presented and the calculated values for the porosity, pore diameter and specific surface area are compared with results from air permeability and nitrogen adsorption measurements. The agreement is acceptable taking into account the simplifications and the inaccuracy of the methods.
Keywords:To whom correspondence should be addressed.
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