| 异丁腈合成2-异丙基-4-甲基-6-羟基嘧啶的研究 |
| |
| 引用本文： | 郑志明.异丁腈合成2-异丙基-4-甲基-6-羟基嘧啶的研究[J].精细化工中间体,2001,31(2):21-22. |
| |
| 作者姓名： | 郑志明 |
| |
| 作者单位： | 浙江永农化工研究所,浙江,温州,325024 |
| |
| 摘 要： | 介绍了以异丁腈为原料 ,与氯化氢、氨气反应合成异丁脒盐酸盐 ,在水溶液中同乙酰乙酸甲酯反应合成 2 异丙基 4 甲基 6 羟基嘧啶的工艺路线 ,总收率达到 83% ,含量达到 98%以上。
|
| 关 键 词： | 异丁腈 乙酰乙酸甲酯 2-异丙基-4-甲基-6-羟基嘧啶 |
| 文章编号： | 1009-9212(2001)02-0021-02 |
| 修稿时间： | 2001年2月6日 |
Study on the Process of Isobutyronitrile to 2-isopropyl-4-methyl-6-hydroxypyridine |
| |
| ZHENG Zhi,ming.Study on the Process of Isobutyronitrile to 2-isopropyl-4-methyl-6-hydroxypyridine[J].Fine Chemical Intermediates,2001,31(2):21-22. |
| |
| Authors: | ZHENG Zhi ming |
| |
| Abstract: | A synthetic route for preparation of 2 isopropyl 4 methyl 6 hydroxypyridine is introduced in this article, which is started with Isobytyronitrile, reacting with Hydrogen Chloride and free ammonia to make Isobutyl amidine hydrochioride, then the said product is synthesed byreaction with Methyl Acetoacetate in water solution. The total yield is 83%, and purity is up to 98% min. |
| |
| Keywords: | isobytyronitrile methyl acetoacetate 2 isopropyl 4 methyl 6 hydroxypyridine |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
