Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds |
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| Affiliation: | 1. Department of Manufacturing and Materials Engineering, Faculty of Engineering International Islamic University Malaysia, 50728 Kuala Lumpur, Malaysia;2. State Ministry for Research and Technology, Jakarta 10340, Indonesia;3. Centre of Advanced Manufacturing & Material Processing (AMMP), Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia;4. Division of Neurosurgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia;5. Centre for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia;6. Kyushu University, Fukuoka, Japan;1. Institute of Materials Physics, Hangzhou Dianzi University, Hangzhou 310018, PR China;2. College of Physics and Electrical Engineering, Anyang Normal University, Anyang 455000, PR China |
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| Abstract: | This study investigates the properties of sol-gel derived sodium (Na)-doped hydroxyapatite (HA) powder. Different amounts of Na (1, 5, 10 and 15 mol%) were prepared and the sintered bodies were characterized to determine the current phases, microstructural evolution and mechanical properties. X-ray diffraction analysis reveals that a phase pure HA of crystallite sizes, which varied from 35 nm to 65 nm, was obtained in the synthesized powder after calcining from 500 °C to 1000 °C. Scanning electron microscopy examination shows evidence of larger particle sizes, particularly in samples that contain higher amounts of Na concentration. The resultant powders were subsequently used to prepare porous NA-doped HA bodies through a polymeric sponge method. The addition of 5% Na resulted in a porous body with 27% porosity and was beneficial in enhancing the compressive strength of HA 17-fold compared with undoped HA. The prepared scaffold also shows suitable pore interconnectivity with pore sizes that vary between 100 and 300 µm which is suitable for use as porous bone substitutes. |
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| Keywords: | Porous hydroxyapatite Sodium doping Mechanical properties |
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