Modulation of [3H]mazindol binding sites in rat striatum by dopaminergic agents |
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Authors: | K Ikawa A Watanabe S Kaneno M Toru |
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Affiliation: | Department of Surgery, Saiseikai Central Hospital. |
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Abstract: | A 57-year-old male presented with palpitations and dyspnea on exertion. Examination of the peripheral blood and bone marrow showed pancytopenia with marked red cell aplasia. Hypogammaglobulinemia was also recognized. Chest X-ray and CT showed a mass in the anterior mediastinum. A biopsy showed thymoma. Two months after admission, the patient died of sepsis secondary to worsening pancytopenia and hypogammaglobulinemia. Autopsy showed non-invasive spindle cell type thymoma and a marked decrease of hematogenous cells. Review of the literature indicates that pancytopenia associated with thymoma is resistant to all forms of treatment and its prognosis is poor. |
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