| 摄食壳聚糖对小鼠体内铅水平的影响 |
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| 引用本文： | 覃彩芹,曾林涛,李伟. 摄食壳聚糖对小鼠体内铅水平的影响[J]. 食品科学, 2009, 30(1): 246-248. DOI: 10.7506/spkx1002-6630-200901058 |
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| 作者姓名： | 覃彩芹 曾林涛 李伟 |
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| 作者单位： | 1.孝感学院天然多糖研究室 2.武汉大学 生物质资源化学与环境生物技术湖北省重点实验室 |
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| 基金项目： | 国家自然科学基金，湖北省教育厅科研项目 |
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| 摘 要： | 采用壳聚糖含量为1.05% 的饲料喂食小鼠90d，喂食的四种壳聚糖分别是高分子量壳聚糖(HCS)(重平均分子量Mw7.60 × 105，脱乙酰度(DDA) 85.5%、中分子量壳聚糖(MCS)(Mw3.27 × 104，DDA85.2%)、壳寡糖(COS)(Mw0.99 × 103，DDA 85.7%)和水溶性壳聚糖(WSC)(Mw3.91 × 104， DDA52.6%)。喂养期间，小鼠无非正常症状和死亡发生。实验结果表明，喂食HCS 对小鼠的肝、脾、心脏和肾脏中的铅含量几乎无影响，COS 和WSC使小鼠的肝、脾和心脏中的铅含量有所降低。但是，MCS 却明显增加了肝脏中铅含量。
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| 关 键 词： | 壳聚糖 小鼠 铅 |
| 收稿时间： | 2008-01-25 |
Effect of Dietary Chitosan on Level of Lead in Mice |
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| QIN Cai-qin,ZENG Lin-tao,LI Wei. Effect of Dietary Chitosan on Level of Lead in Mice[J]. Food Science, 2009, 30(1): 246-248. DOI: 10.7506/spkx1002-6630-200901058 |
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| Authors: | QIN Cai-qin ZENG Lin-tao LI Wei |
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| Affiliation: | (1.Laboratory of Natural Polysaccharides, Xiaogan University, Xiaogan 432000, China ；2.Key Laboratory of Biomass-ResourceChemistry and Environmental Biotechnology of Hubei, Wuhan University, Wuhan 430072, China) |
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| Abstract: | 1.05% of 4 kinds of dietary chitosans with different molecular weights (Mw) and degrees of deacetylation (DDA) (high molecular weight chitosan HCS with Mw 7.60×105 and DDA 85.5%, middle molecular weight chitosan MCS with Mw 3.27×104 and DDA 85.2%, chitooligomer COS with Mw 0.99×103 and DDA 85.7%, and water-soluble chitosan WSC with Mw 3.91×104 and DDA 52.6%) were fed to mice for 90 days. No abnormal symptoms, clinical signs or deaths were observed during the feeding period. The body weights of mice between chitosan groups and control group show no significant difference. HCS almost has no effect on the levels of lead in liver, spleen, heart and kidney. COS and WSC decrease the levels of lead in liver, spleen and heart. However, MCS significantly increases the level of lead in liver. |
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| Keywords: | chitosan mouse lead |
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