Immunosuppressive peptides corresponding to MHC class I sequences |
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Authors: | C Clayberger AM Krensky |
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Affiliation: | Department of Cardiothoracic Surgery, Stanford University, CA 94305-5247, USA. |
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Abstract: | The induction of tolerance is a long-standing goal in transplantation. Intact MHC molecules, or fragments of them, are being used to render T cells unresponsive both in vitro and in vivo. Elucidation of the mechanisms underlying the effects of these treatments should aid the design of novel therapies for transplantation. |
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