| 尿素包合法富集鱼油中的EPA和DHA的工艺研究 |
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| 引用本文： | 杜起光,王志祥,田龙. 尿素包合法富集鱼油中的EPA和DHA的工艺研究[J]. 化工时刊, 2009, 23(9): 13-15. DOI: 10.3969/j.issn.1002-154X.2009.09.003 |
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| 作者姓名： | 杜起光 王志祥 田龙 |
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| 作者单位： | 中国药科大学制药工程教研室,江苏,南京,210009;中国药科大学制药工程教研室,江苏,南京,210009;中国药科大学制药工程教研室,江苏,南京,210009 |
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| 摘 要： | 运用尿素包合法富集鱼油中的EPA和DHA。考察了尿脂比、反应温度、结晶温度和结晶时间对EPA和DHA总纯度的影响。随尿脂比的增大，总纯度先增大后趋于稳定，适宜的尿脂比为2．5：1。随反应温度的升高，总纯度逐渐增大，适宜的反应温度为55℃。随结晶温度的降低，总纯度逐渐增大，适宜的结晶温度为0℃。随结晶时间的增大，总纯度先增大后趋于稳定，适宜的结晶时间为1h。
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| 关 键 词： | 鱼油 EPA DHA 尿素包合 富集 |
Enrichment of EPA and DHA from Fish Oil by Urea Complexation |
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| Du Qiguang Wang Zhixiang Tian long. Enrichment of EPA and DHA from Fish Oil by Urea Complexation[J]. Chemical Industry Times, 2009, 23(9): 13-15. DOI: 10.3969/j.issn.1002-154X.2009.09.003 |
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| Authors: | Du Qiguang Wang Zhixiang Tian long |
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| Affiliation: | Du Qiguang Wang Zhixiang Tian long (Department of Pharmaceutical Engineering, China Pharmaceutical University, Jiangsu Nanjing 210009) |
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| Abstract: | Urea complexation was carried out to enrich Eicosapentaenoic Acid and Docosahexaenoic Acid from fish oil. In this process, the effects of response variables including urea -to -fatty acid ratio, reaction temperature, crystallization temperature, and crystallization time on purification of EPA and DHA were studied by single factor experiment. With the increase of urea - to - fatty acid ratio, the total purification firstly increased and then stabilized, the proper urea -to -fatty acid ratio was 2.5： 1. With the increase of reaction temperature, the total purification increases, the proper reaction temperature was 55℃. With the decrease of crystallization temperature, the total purification increased, the proper crystallization temperature was 0℃. With the increase of crystallization time, the total purification firstly increased and then stabilized, the proper crystallization time was 1 h. |
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| Keywords: | EPA DHA |
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