| Affiliation: | 1. State Key Laboratory of Fine Chemicals, Engineering Laboratory for Petrochemical Energy-efficient Separation Technology of Liaoning Province, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, Liaoning, China;2. State Key Laboratory of Fine Chemicals, School of Petroleum and Chemical Engineering, Dalian University of Technology at Panjin, Panjin, 124221, Liaoning, China;3. State Key Laboratory of Fine Chemicals, Engineering Laboratory for Petrochemical Energy-efficient Separation Technology of Liaoning Province, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, Liaoning, China State Key Laboratory of Fine Chemicals, School of Petroleum and Chemical Engineering, Dalian University of Technology at Panjin, Panjin, 124221, Liaoning, China |
| Abstract: | Herein, a novel hollow fiber membrane-assisted antisolvent crystallization (MAAC) was proposed to enhance the mass transfer control over the antisolvent crystallization. A polyethersulfone membrane module was introduced as the key device for antisolvent transfer and solution mixing. An antisolvent liquid film layer was formed on the membrane surface and mixed with the solution. The liquid film also prevented the membrane from directly contacting with crystallization solution. By controlling both the shell side flow velocity and the antisolvent transfer, the antisolvent permeation rate achieved sensitive, stable, and accurate control during long-term and repeated utilization. The interfacial mass transfer rate of MAAC was 0.66 mg cm−2 s−1, which was only 1/50 that of conventional droplet antisolvent crystallization. MAAC also provided crystal products with better morphologies and narrower size distributions than the conventional process. The stable performances of MAAC in terms of its accurate antisolvent mass transfer and antifouling capabilities were also highlighted. © 2018 American Institute of Chemical Engineers AIChE J, 65: 734–744, 2019 |
